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Every fifth person is a carrier of the gene of longevity and mind - VIDEO PDF Print E-mail
Thursday, 29 January 2015 14:27

Variations of genes, known as alleles, often operate on the principle of the volume control on the speakers - they increase or decrease the risk of developing certain diseases. A new study by researchers at the University of California at San Francisco (UCSF) has been devoted to a specific allele carriers which not only live longer, but also have large brains in the truest sense of the word.

Variation in the gene KLOTHO can help us to predict the health of the brain and to find ways to protect people from the ravages of age-related diseases such as Alzheimer's disease and other dementias - said in a press release UCSF.

The gene encodes a protein KLOTHO Klotho, produced in the brain and kidney. From there, it helps regulate many different processes occurring in the human body. Since the mutated gene can take several alternative forms, one of them may be an allele KL-VS, single copy of which, as the researchers note, occurs in one out of five people. It is associated with the correct functioning of the heart and kidneys, and is also responsible for longevity. About 3 percent of people in the world have two copies of the KL-VS, conversely, that is associated with a shorter life.

Previously, it was found that people of middle and old age with a single copy of KL-VS show much better results in the tests on the brain. Study of KL-VS allele showed a stronger connection between neurons, which improves learning and memory.



Carriers of a single copy of KL-VS there is an increase in brain volume in the anterior part, involved in the planning and decision-making than people with two copies of the gene, or none at all.

Area of the brain, strengthening the variation in the gene KLOTHO, vulnerable to aging and certain neuropsychiatric diseases, including - schizophrenia, depression, substance abuse, and frontotemporal dementia. In this case, the larger the size, the better the brain - researchers say.

The study was published in the journal Annals of Clinical and Translational Neurology.


НАЖМИТЕ ЗДЕСЬ ДЛЯ ПРОСМОТРА ВСЕГО СПИСКА НОВОСТЕЙ О НЕОБЫЧНЫХ ЯВЛЕНИЯХ>>>

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