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Animals and people without pain live longer- VIDEO PDF Print E-mail
Sunday, 25 May 2014 10:28

Scientists have long suspected, that between life expectancy and pain there is a relationship. Previous studies have shown, that the flies and worms, which are absent due to mutations certain sensory neurons live longer than their counterparts. Now, researchers at the University of California at Berkeley (University of California) not only confirmed these suspicions example mice, but also learned how to use the pain receptors to return the animal an youth. Back in 2008 Andrew Dillin and his colleagues found, that mice in which was deleted TRPV1 gene, responsible for the activation of sensory receptors while taking a hot or spicy foods, even very fatty diet slowly gain weight . Scientists decided to test does not affect whether the presence or absence of this gene on the lifespan of the animals and found that males lacking TRPV1, lived 12% longer than usual. In females, life expectancy increased more substantially - by 16%. Trying to figure out the reasons for such rejuvenation Dillin team found, that without receptor TRPV1 can not form two proteins that are part of the neuropeptide CGRP. This substance inhibits the body's production of insulin. Therefore, when the formation of CGRP decreases produce more insulin. The result is a useful side effect of the whole metabolism. Of course, the complete absence of sensory receptors has a negative side, because the animals do not feel pain and can cause injury. Scientists believe, that this circumstance caused the preservation of these properties in the course of natural selection. "Our results suggest that the pharmacological manipulation of TRPV1 and receive appropriate drugs can prevent age- weakening metabolism and increase life expectancy ,"- says Dillin in a university news release. Meanwhile, other works indicate the role of CGRP in the life of animals and humans. So, the most long-lived rodents - naked mole rats (Heterocephalus glaber), which live up to 30 years, this neuropeptide is completely absent. And people who suffer from migraine, its content in sensory neurons increases, VIDEO:


НАЖМИТЕ ЗДЕСЬ ДЛЯ ПРОСМОТРА ВСЕГО СПИСКА НОВОСТЕЙ О НЕОБЫЧНЫХ ЯВЛЕНИЯХ>>>

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